No date has been set for the 2021 game, which will be the first in a new five-year contract between the Pac-12 and ACC.
The Holiday Bowl was played from its inception in 1978 until 2019 in Mission Valley at what was known as San Diego/Jack Murphy/Qualcomm Stadium.
With no fans allowed last fall, San Diego State moved its home college football games to an MLS stadium in the Los Angeles suburb of Carson and began tearing down Qualcomm Stadium so it could begin building a new 35,000-seat stadium set to open in 2022.