Vrabel announced the news via a Zoom call with reporters on Sunday following the Titans’ 34-3 win over the Buccaneers in their second preseason game.
Vrabel, a three-time Super Bowl champion as a player with the Patriots, is entering his fourth season as Titans head coach.
While he quarantines away from the team, Vrabel said he will rely on assistant coaches Jim Haslett and Jim Schwartz, who both have past experience as NFL head coaches, along with special teams coordinator Craig Aukerman.
Vrabel said that he will receive another COVID-19 test on Monday and needs two negative tests to avoid a 10-day quarantine.