Guillermo Heredia struck out looking, Kevan Smith struck out swinging and Ian Anderson struck out looking to end the third.
After getting Adrianza on a grounder to first to start the fourth inning, Lopez allowed three hits in the next four at-bats.
The New York Mets’ Jacob deGrom and Philadelphia Phillies’ Aaron Nola, who also pitch in the National League East, each struck out nine consecutive batters earlier this season.