Vladimir Guerrero Jr., Bo Bichette, Lourdes Gurriel Jr., Cavan Biggio, Rowdy Tellez and Semien also went deep for the Blue Jays, a day after they belted five homers in a 7-2 victory.
“Honestly, I don’t know,” winning pitcher Robbie Ray said, when asked what he’d do if he was facing Toronto’s lineup.
Semien’s drive into the batters’ eye in center made it 5-0 in the second, prompting loud boos from the Fenway Park crowd.
Toronto broke it open with four runs in the fourth and four more in the fifth, making it 13-1.
“It’s really fun, when you hit a fly ball that’s a regular fly ball in other parks, here it a base hit, maybe a double,” Hernández said.
Blue Jays: Placed Saturday’s winning pitcher, Steven Matz, on the COVID-19-related injured list.